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How Unsafe Are Viagra and Cialis Impotence Pills?

This issue has raised considerable concern. Within the first year of Viagra's release, the FDA documented the deaths of 130 men who were taking the drug. Most of these men died of heart disease. Some of them were taking nitrates (nitroglycerin), a type of heart medication that is known to have devastating side effects when combined with Viagra. In other men, it is unclear whether Viagra contributed to their death. One theory is that heart problems may be triggered by vigorous sexual activity rather than by Viagra itself.

Subsequent trials suggest that men with heart disease should be cautioned against use of Viagra and related drugs. PDE5 drugs should never be combined with nitro - glycerin or other nitrates . This can cause a life-threatening drop in blood pressure in men without heart problems also. If you have chest pain and have taken Viagra within the past 24 hours tell your doctor. A drop in blood pressure may also happen if PDE5 drugs are mixed with alpha blocker drugs, and sex party drugs known as poppers like amyl nitrate or butyl nitrate. Viagra should not be taken by men with the following medical conditions :

  • *Heart-attack/stroke within six years
  • *Unstable-heart disease or heart failure
  • *High-blood pressure with multiple drugs
  • *Very-high or very low blood pressure
  • *Liver/kidney disease
  • *Retinitis pigmentosa (a rare eye disorder)

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Men who have high blood pressure, high cholesterol, diabetes or other risk factors for heart disease and who don't lead an active lifestyle should have a stress test before resuming vigorous sexual activity and using Viagra.

Talk with your doctor if you are unsure whether Viagra is safe for you as PDE5 drugs can interact with medications other than nitrates, so give your doctor an accurate list of the drugs you take.


What are the side effects?

PDE5 drugs have number of side effects such as headache, light headedness, feeling dizziness, heat flushing and loss of vision. Many men choose not to take these drugs because of these side effects. Cialis, since it stays in the body for up to 2 days also causes prolonged painful erections (priapism) sometimes.

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Prescribed Viagra Is Not For Everyone

Viagra is one of the most prescribed drugs in years, with more than 1 million new prescriptions since being approval by the U.S. FDA. Known as sildenafil citrate, it is the first effective erectile dysfunction drug that comes in a pill. It allows the body's natural system for creating erections, causing the smooth muscles in the penis to relax and fill with blood. It's effective for 70 percent of men in clinical trials. Now with a growing number of deaths reported among men who have used Viagra, health care specialist are stating that Viagra is not be for everyone.

The death of a retired airline executive, which occurred May, came after four other deaths of men using Viagra from heart attack or stroke described in reports to the FDA. Other Viagra patients died in the clinical trials leading up to the drug's introduction. The deaths, mark a health risk for users of Viagra known both by the FDA and Pfizer.

Men enjoying sex again after some time of impotence can often overtax their system. That risk is high for men with impotence, since some of the causes of the condition, high blood pressure, cardiovascular, and diabetes disease, put them at high risk of a heart attack or stroke.

The FDA said that the nine preapproval deaths mean we will continue our monitoring and expects to see more deaths , in part because of the drug's high risk. He added that the number of cases seen so far is a major concern.


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Viagra®:
Viagra® (Sildenafil Citrate) is used as a therapy for erectile dysfunction, and is administered orally. Sildenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).

The many side-effects of Viagra® have been tabulated below:
Adverse Event Percentage of Patients Reporting Event Side Effects caused by Viagra and Cialis
VIAGRA N=734 PLACEBO N=725
*Headache 16% 4%
*Flushing 10% 1%
*Dyspepsia 7% 2%
*Nasal Congestion 4% 2%
*Urinary Tract Infection 3% 2%
*Abnormal Vision 3% 0%
*Diarrhea 3% 1%
*Dizziness 2% 1%
*Rash 2% 1%

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Besides these Viagra also has serious interactions with other drugs.

What drugs are known to adversely interact with Viagra?
•Viagra should not be taken if nitrates are also taken . Nitrates include:

•nitroglycerin
•isosorbide dinitrate and
•isosorbide mononitrate , or
•sex drugs such as amyl nitrate or nitrite poppers


• Your doctor must be informed before you use Viagra, if you use some of the following drugs:

•bosentan ;
•cimetidine;
•antibiotic such as erythromycin;
•doxazosin, prazosin, Terazosin;
•HIV drugs
•antifungal medication such as itraconazole or ketoconazole;
•carbamazepine, phenobarbital, or phenytoin; or
•Rifampin or rifabutin .

There might be others that affect Viagra also. Tell your doctor all details of your drugs, both prescribed and OTC. This includes drugs prescribed by other doctors.

Cialis®:

Cialis® (tadalafil) is also a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), and used in the treatment of ED.

Like Viagra®, Cialis® too has an enormous list of side effects as listed below:

  Placebo Tadalafil 5 mg Tadalafil 10 mg Tadalafil 20 mg
Adverse Event (N=476) (N=151) (N=394) (N=635)
Headache 5% 11% 11% 15%
Dyspepsia 1% 4% 8% 10%
Back Pain 3% 3% 5% 6%
Myalgia 1% 1% 4% 3%
Nasal congestion 1% 2% 3% 3%
Flushing* 1% 2% 3% 3%
Pain in limb 1% 1% 3% 3%


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The following are the drug interactions caused with Cialis®:

• cimetidine (Tagamet, Tagamet HB);
• erythromycin (E-Mycin, Eryc, Ery-Tab) or clarithromycin (Biaxin);
• doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin);
• HIV medicines such as amprenavir (Agenerase), tipranavir (Aptivus), darunavir (Prezista), efavirenz (Sustiva), nevirapine (Viramune), indinavir (Crixivan), saquinavir (Invirase, Fortovase), lopinavir/ritonavir (Kaletra), fosamprenavir (Lexiva), ritonavir (Norvir), atazanavir (Reyataz), or nelfinavir (Viracept);
• itraconazole (Sporanox) or ketoconazole (Nizoral);
• carbamazepine (Tegretol), phenobarbital (Luminal), or phenytoin (Dilantin); or
• rifampin (Rifadin, Rimactane).

*Source, drugs.com

In spite of all the above side effects and risks involved in taking Viagra® or Cialis®, both come with really high prices, and the damage extends even to your wallet.

ProVIGRAX, available at just $1 for a single tab, is a much safer and cost effective alternative.
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